Antibiotic use may up heart attack, stroke risk in women

The possible reason why the antibiotic use is linked to an increased risk of cardiovascular disease is because of the antibiotics of the balance, the researchers said.
The possible reason why the antibiotic use is linked to an increased risk of cardiovascular disease is because of the antibiotics of the balance, the researchers said.

  1. Women aged 60 or older who took antibiotics for two months or more of the 
  2. greatest risk of cardiovascular disease, but long duration of antibiotic use was also 
  3. associated with a increased risk if taken during middle age (age 40-59). (Photo: 
  4. Thinkstock Images) Women who take 
  5. antibiotics over a long period of time are at increased risk of heart attack or stroke, a 
  6. study claims.

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The study, published in the European Heart Journal, found that women aged 60 or older who took antibiotics for two months or
more of the greatest risk of cardiovascular disease, but long duration of antibiotic use was also associated with a increased risk. age (age 40-59)

The researchers could find no increased risk from antibiotic use by young adults aged between 20-39 years.

The possible reason why the antibiotic use is linked to an increased risk of cardiovascular disease is because of the antibiotics of the balance, the researchers said.

"Antibiotic use is the most critical factor in altering the balance of microorganisms in the gut. Previous studies have shown a link between alterations in the microbiotic environment of the gut and inflammation and narrowing of the blood vessels, stroke and heart disease, "said Lu Qi, director of the Tulane University in the US.

The researchers studied 36,429 women who took part in the Nurses' Health Study, which has been running in the USA since 1976. The current study looked at data from 2004 to June 2012.

In 2004 the women were aged 60 or older, and they were asked about their use of antibiotics when they were young (20-39), middle age (40-59) or older (60 and older).

The researchers categorized them into four groups: those who had never taken antibiotics, those who had taken them for periods of less than 15 days, 15 days to two months, or for two months or longer.

During an average follow-up period of nearly eight years, during which time the women continued to complete the questionnaires every two years, 1,056 participants developed cardiovascular disease.

The researchers found that women who used antibiotics for periods of two months or longer in late adulthood were 32 per cent more likely to develop cardiovascular disease than women who did not use antibiotics.

Women who took antibiotics for longer than two months in middle age had a 28 percent increased risk compared to women who did not.

These findings mean that among women who take antibiotics for two months or more in late adulthood, Six Women feet 1,000 would develop a cardiovascular disease, compared to three per 1,000 among Women Who extent not Takein antibiotics.

"By the investigation of the duration of antibiotic use in various stages of adulthood, we have found an association between long-term use in middle age and later life and an increased risk of stroke and heart disease during the following eight years," said Yoriko Heianza, a Research fellow at Tulane University

"This is an observational study and so it can not show that antibiotics cause heart disease and stroke, only that there is a link between them," Qi said.

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"It's possible that women who reported more antibiotic use might be sicker in other ways that we were unable to measure, or there may be other factors that could affect the results that we have not been able take account of," Hey Said.

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